Chemistry is a science, the study of the chemistry between you and me... isn't that how some song goes or something? I'm getting it as mangled as Sleeping With Other People -- which I keep thinking acronymizes (sure that's a word) to SLOP, though it doesn't, though that I keep thinking it does should tell you where I'm coming from -- gets chemistry, for it's all the hell off all over this movie. It has to do with writing -- it never makes feels anything approaching believable that the main characters (played by Allison Brie and Jason Sudeikis) stay friends when it's against all their best interests. It has to do with the casting -- Brie and Sudeikis have too much of the same wisecracking sidekick thing going on; there's not much bounce off each other... it's more like a resigned collapse on the couch after eating too much; right passed comfortable and into belches-that-kinda-hurt territory.
And this is the film that finally convinced me Jason Sudeikis, who very well might be a swell fella in real life, has literally no business, zero percent, playing characters that aren't assholes. He can play variations - sexy asshole, or asshole asshole - but nice-guy's a nope, a not it. There's nothing but doggedly-insincere oozing from all of his pores. I suppose that's chemistry of it's own kind. The whole recipe's all wrong, and the ingredients just collapse in upon themselves, a black hole of bitter icing with no under cake to speak of.